Police are currently investigating after two males were spotted throwing rocks at a bus at Rozelle this afternoon.
At roughly 4.15pm, police were called to the Western Distributor at the Anzac Bridge near the Pyrmont Bridge off ramp.
There were reports that rocks were thrown at a bus, causing a window to shatter and injuring three people.
The males then fled from the scene.
Paramedics have three people for minor injuries, and two have been transported to hospital.
One is a female patient in her 30s or 40s with a possible eye injury.