GWS players Devon Smith, Matt Kennedy and Nathan Wilson have all requested to explore a trade.
The Giants confirmed on Thursday that Smith and Kennedy would seek out other opportunities elsewhere, while Wilson expressed his desire to return home to Western Australia.
Smith and Kennedy are out of contract, with Wilson tied to the Giants until the end of 2018.
GWS head of football Wayne Campbell confirmed the news.
"We are sympathetic to Nathan’s situation and we understand Devon and Matt’s wish to explore opportunities during the trade period,” he told GWS's website.
"We’ll now work with the respective players and their managers to arrive at the most appropriate outcome."