UPDATE: 58 Killed, Over 500 Injured In Las Vegas Shooting

WHAT WE KNOW: 

What: The Route 91 Harvest Festival was inundated with a hail of gunfire which witnesses say lasted more than 15 minutes, killing at least 58 people and injuring over 500. 

Who: "Lone gunman" Stephen Paddock, 64, fired on the crowd from his 32nd floor Mandalay Hotel room before killing himself. Police have ruled out Australian woman Marilou Danley as a suspect. She's understood to have lived with Paddock and was believed to be his girlfriend. 

Where: The open-air festival was on the Las Vegas strip, next to the iconic Las Vegas Boulevard. Paddock's residence was in Mesquite, 130km northeast of Las Vegas.

Why: Police say they're still investigating the motive behind the shooting and have not yet labelled it domestic terrorism. Early this morning (AEST) officers stormed his Mesquite home and are currently processing it. They say he has no links to international terror groups.

UPDATE 7:40am – Foreign Minister Julie Bishop has told Triple M's Hot Breakfast there is no indication any Australians have been killed or injured in the shooting.

She told Eddie, Mick and Darce the Department of Foreign Affairs is making "urgent enquiries" including contacting hospitals and local authorities to confirm.

"There could be quite a number of Australians in the vicinity," she said. "It is a very popular tourist destination." 

The Foreign Minister has confirmed Australian woman Marilou Danley is no longer a person of interest, according to Las Vegas police.  

Anyone concerned about a loved one can call the Department's hotline on 1300 555 135. 

UPDATE 6:10am – Witness Brian Hodge, who was staying in the room next to Paddock, spoke to Triple M's Hot Breakfast this morning. Listen to what he had to say: 

EARLIER – The iconic streets of Las Vegas have fallen silent as Nevada comes to grips with the deadliest mass shooting in U.S. history.

58 people are dead and more than 515 have been injured, according to the latest information from Las Vegas police.

64-year-old gunman Stephen Paddock, who was found with more than ten rifles in his room, peppered bullets from an automatic rifle onto the crowd of an open-air country music festival from the 32nd floor of the Mandalay Hotel. Witnesses said it lasted at least five minutes.

"There [were] people in front of us that were getting shot," one witness told CNN. "As you were hearing shots going off you were hearing them hit the ground." 

President Donald Trump led a moment of silence for the victims, labelling it an "act of pure evil." 

No motive for the massacre has been identified yet but the man has no links to international terrorism, according to Las Vegas police.

"There's motivating factors associated with terrorism other than a distraught person intending to cause mass casualties," said Sheriff Lombardo. 

"Before we label with that it will be a matter of process." 

Several hours ago police stormed his Mesquite home, 130km northeast of Las Vegas.

Earlier police appealed for information regarding 62-year-old Australian woman Marilou Danley, who is understood to have formerly lived on the Gold Coast.

Detectives have made contact with the woman – who they believe was his girlfriend and lived with him – and cleared her of any involvement. 

McCarran International Airport officials say all flights in and out have been temporarily halted.