UPDATE: Spencer Street has now reopened following today's incident.
EARLIER: Spencer Street's closed in both directions as crews work to remove a three tonne load of glass hanging from a broken down crane.
It's happening between Lonsdale and LaTrobe Streets.
Andrew Crook from Vicroads says it's likely to stay that way for a while:
“It’s likely this work will continue for a few hours, maybe even impacting the afternoon peak”